{"product_id":"igf-1-lr3","title":"IGF-1 LR3","description":"\u003ch3\u003eSynthetic Peptide for Growth Factor Research\u003c\/h3\u003e\n\u003ch3\u003eTechnical Overview\u003c\/h3\u003e\n\u003cp\u003eIGF-1 LR3 1mg is a synthetic peptide compound developed for laboratory research involving insulin-like growth factor signaling and somatomedin pathway analysis, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying IGF-1 receptor activation profiles, PI3K\/Akt and MAPK pathway dynamics, and related biochemical mechanisms.\u003c\/p\u003e\n\u003cp\u003eIGF-1 LR3 is a recombinant 83-residue IGF-1 analog with arginine substituted for glutamic acid at position 3 and an additional 13-residue N-terminal extension. These modifications dramatically reduce binding to IGF binding proteins (IGFBP-1 through IGFBP-6), increasing the proportion of bioavailable peptide for receptor interaction in cell-culture systems.\u003c\/p\u003e\n\u003cp\u003eResearchers utilize this analog to study cell-cycle progression, protein synthesis, and survival signaling in myoblast, hepatocyte, and stem-cell models. Its reduced IGFBP affinity makes it a preferred tool for distinguishing receptor-mediated effects from binding-protein-mediated sequestration.\u003c\/p\u003e\n\u003cp\u003eThis compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.\u003c\/p\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCompound Name:\u003c\/strong\u003e IGF-1 LR3\u003cbr\u003e\u003cstrong\u003eStrength:\u003c\/strong\u003e 1mg\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99% (HPLC Verified)\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e Lyophilized Peptide Powder\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Research Compound\u003cbr\u003e\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Suitable for laboratory assay preparation.\u003c\/p\u003e\n\u003ch3\u003eNotice\u003c\/h3\u003e\n\u003cp\u003eProvided as a reference material for scientific investigation only.\u003c\/p\u003e","brand":"American Peptides","offers":[{"title":"1 mg","offer_id":48615147733147,"sku":"IGF1-1","price":85.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/2876\/6619\/files\/igf-1-lr3-normalized.png?v=1780880407","url":"https:\/\/www.americanpeptides.us\/products\/igf-1-lr3","provider":"American Peptides","version":"1.0","type":"link"}