{"product_id":"semaglutide","title":"SEMAGLUTIDE","description":"\u003ch3\u003eSynthetic Peptide for Metabolic Pathway Research\u003c\/h3\u003e\n\u003ch3\u003eTechnical Overview\u003c\/h3\u003e\n\u003cp\u003eSemaglutide 20mg is a synthetic peptide compound developed for laboratory research involving incretin signaling and GLP-1 receptor pharmacology, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying receptor-agonist binding profiles, downstream cAMP and insulinotropic signaling responses, and related biochemical mechanisms.\u003c\/p\u003e\n\u003cp\u003eSemaglutide is a long-acting GLP-1 receptor analog featuring an Aib substitution at position 2 to confer DPP-IV resistance and a fatty-acid (C18 diacid) side chain at Lys26 that promotes albumin binding for extended plasma residence. In research models, it is investigated as a tool compound for probing GLP-1R conformational dynamics and beta-arrestin recruitment.\u003c\/p\u003e\n\u003cp\u003eInvestigators commonly use this analog to dissect incretin-axis signaling in pancreatic islet preparations, hypothalamic appetite-regulation studies, and gastric motility models. Comparative work alongside native GLP-1 and tirzepatide enables receptor-selectivity and biased-agonism characterization.\u003c\/p\u003e\n\u003cp\u003eThis compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.\u003c\/p\u003e\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCompound Name:\u003c\/strong\u003e Semaglutide\u003cbr\u003e\u003cstrong\u003eStrength:\u003c\/strong\u003e 20mg\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99% (HPLC Verified)\u003cbr\u003e\u003cstrong\u003eAppearance:\u003c\/strong\u003e Lyophilized Peptide Powder\u003cbr\u003e\u003cstrong\u003eFormat:\u003c\/strong\u003e Research Compound\u003cbr\u003e\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Suitable for laboratory assay preparation.\u003c\/p\u003e\n\u003ch3\u003eNotice\u003c\/h3\u003e\n\u003cp\u003eProvided as a reference material for scientific investigation only.\u003c\/p\u003e","brand":"American Peptides","offers":[{"title":"20 mg","offer_id":48615147667611,"sku":"SEMA-20","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/2876\/6619\/files\/semaglutide-normalized.png?v=1780880449","url":"https:\/\/www.americanpeptides.us\/products\/semaglutide","provider":"American Peptides","version":"1.0","type":"link"}