Research Library

Education for serious researchers.

Lab-tested guides on peptide quality, COA interpretation, lyophilization, storage, and the science behind what we ship. Compliant, accurate, written by people who handle these compounds every day.

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8 POSTS
Sterility Testing for Research Peptides: USP <71> Fundamentals
Contamination

Sterility Testing for Research Peptides: USP <71> Fundamentals

How the compendial sterility test works under USP <71> — and why a sample can pass it and still fail endotoxin testing.

Jun 06, 2026 � 10 MIN
Endotoxin Testing Explained: LAL, rFC, and the Limulus Story
Endotoxin

Endotoxin Testing Explained: LAL, rFC, and the Limulus Story

The biology behind one of analytical chemistry's most unlikely test methods — and why endotoxin testing matters even when steri...

Jun 06, 2026 � 10 MIN
Mass Spectrometry (LC-MS) for Peptide Identity Confirmation
Analytical

Mass Spectrometry (LC-MS) for Peptide Identity Confirmation

Why LC-MS is the analytical step that closes the gap left by purity measurements — and how to read a peptide mass spectrum.

Jun 06, 2026 � 11 MIN
What Is HPLC? A Researcher's Guide to Peptide Purity Verification
Analytical

What Is HPLC? A Researcher's Guide to Peptide Purity Verification

How the standard analytical method for peptide purity actually works — and why the chromatogram tells a richer story than the h...

Jun 06, 2026 � 11 MIN
Laboratory flasks with American Peptides vial — endotoxin and sterility testing for research peptides
Contamination

Endotoxin and Sterility Testing for Research Peptides: What the Numbers Mean

Endotoxin and sterility are different tests measuring different risks. Both can wreck a cell-based assay long before purity doe...

May 16, 2026 � 4 MIN
Microscope with American Peptides research vials — net peptide content vs purity percentage on a COA
COA

Net Peptide Content vs. Purity %: Reading Beyond the Headline Number on a COA

A 99% pure vial can still contain far less than the labeled mass of actual peptide. Net peptide content is the number that tell...

May 16, 2026 � 4 MIN
Laboratory microscope with American Peptides TB-500 research vials — HPLC vs mass spectrometry COA testing
COA

HPLC vs Mass Spec: What Each Test on a Peptide COA Actually Measures

HPLC measures purity. Mass spec confirms identity. Together they answer two different questions every researcher should care ab...

Apr 27, 2026 � 6 MIN

Quality you can verify, not just claim.

Every batch is tested for purity, identity, sterility, endotoxins, and heavy metals. Every COA is published before you buy.

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